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Longjian Liu, MD, PhD, MSc, FAHA

Associate Professor of Epidemiology and Biostatistics & Interim Chair, Department of Environmental and Occupational Health

Phone: 267.359.6049
College: School of Public Health
Program: Epidemiology and Biostatistics, Center for Health Equality
Email: LL85@drexel.edu
CV: Download CV

Degrees

MD, Shanxi Medical University; MSc in Epidemiology, The University of London School of Hygiene and Tropical Medicine; PhD in Epidemiology, The University of Hong Kong; and MD Postdoctoral Fellow, The University of Arkansas for Medical Sciences

Bio

Dr. Longjian Liu is an associate professor of Epidemiology & Biostatistics, and the Interim Chair of the Department of Environmental and Occupational Health at Drexel University School of Public Health. Prior to joining Drexel, Dr. Liu had training, teaching and research experience in leading universities of China, the United Kingdom, Japan, and the United States. Dr. Liu is a Fellow of the American Heart Association (FAHA).

Dr. Liu teaches Cardiovascular Disease Epidemiology and Prevention, and Epidemiology for Public Health Practice. Dr. Liu also led the course design and taught the online course, entitled “Certificate in Epidemiology and Biostatistics Principles and Methods for Public Health in the 21st Century”. Dr. Liu coauthored the chapter of Cardiovascular Disease Epidemiology for an APHA-published text entitled Chronic Disease Epidemiology and Control (3rd Ed., 2010). Dr. Liu’s teaching philosophy is Students First!

Dr. Liu’s research has focused on epidemiology of cardiovascular disease, diabetes mellitus, premature death, aging and diseases (cognitive and neurodegenerative disorders), and risk factors related to environmental pollution, toxicology, serum biomarkers (lipids and nutrients), medications, drug resistance, and environmental - drug interactions on disease control and prevention. Dr. Liu has research experience in working with several regional, national and international studies. He has over 60 articles published in peer-reviewed journals, with a total Impact Factor score more than 160. The key theories applied in his research are the integrated ecological models, chronic care model and disease preventable models. The overarching goal of his research is to translate research finding to health policy and practice of disease prevention. Four integrated themes are included in his research activities:

(1). Environmental Risk Factors of Cardiovascular Disease and Urban Health: Dr. Liu has involved in the World Health Organization (WHO) - Cardiovascular Disease and Alimentary Comparison (WHO-CARDIAC) Study, the WHO – World Health Surveys (WHS), and the Study on Global Ageing and Adult Health (SAGE). The goal of these studies is to examine environmental risk factors (built environmental, air pollution, healthcare system) and lifestyle-related risk factors for hypertension, heart disease, stroke and diabetes mellitus across nations. Dr. Liu is the Principal Investigator of Drexel (US) - SARI (China) research and Education project on Climate Change, Energy, Low-Carbon, and Urban Health Technology. 

(2). Biomarkers, Drug Resistance and Arterial Aging: Studies of determinants of hypertension, heart disease, stroke, diabetes mellitus, and the consequence of cognitive and neurodegenerative disorders in aging population. Dr. Liu is the Principal Investigator for the study of environmental (E) and drugs, and E - drugs interaction on the risk of heart disease in patients with diabetes mellitus and/or Chronic Kidney Disease. 

(3). Micronutrients, Fatty Acids and Healthy Aging: Studies of the impacts of micronutrients, fatty acids, oxidative stress and inflammation on metabolic disorders, arthrosclerosis and neurodegenerative disorders.

(4). Application of Advanced Analytic Techniques and Mining “Big Data”: Multivariate analysis, mining “big data”, and biological network analysis. Real-time disease risk surveillance and statistical predictive modeling using data from multiple hospitals’ electronic health records, such as Nationwide Inpatient Sample, and National Hospital Discharge Surveys, data from regional, national and international population-based health surveys.

Research Interests

  • Longitudinal data analysis
  • Cancer
  • Nutrition and diet
  • International health in cardiovascular disease epidemiology
  • Asian Health
  • Health Disparities
  • Statistics
  • Cognitive disabilities
  • Epidemiology
  • Aging
  • Asthma
  • Biomarkers
  • Cardiovascular disease
  • Diabetes
  • Molecular epidemiology

Publications

Longjian Liu, Katsuyuki Miura, Akira Fujiyoshi, Aya Kadota, Naoko Miyagawa, Yasuyuki Nakamura, Takayoshi Ohkubo, Akira Okayama, Tomonori Okamura, Hirotsugu Ueshima: Impact of Metabolic Syndrome on the Risk of Cardiovascular Disease Mortality in the United States and in Japan. American Journal of Cardiology, 2014, 113(1):84-89. PMID: 24169008.

Longjian Liu, Yuan An, Ming Chen, Zuolu Liu, Xiaohua Hu, Edgar Chou and Howard J. Eisen: Trends in the prevalence of hospitalization attributable to hypertensive diseases among United States adults aged 35 and older from 1980 to 2007. American J of Cardiology 2013;112:694-699, PMID: 23726180.

Longjian Liu, Fuzhong Xue, Jixiang Ma, Marshal Ma, Yong Long, and Craig J. Newschaffer: Social Position and Chronic Conditions across the Lifespan and Risk of Stroke: A Life-Course Epidemiological Analysis of 22,847 Adult Americans. International Journal of Stroke, 2013;8:50-55, PMID: 23231424.

Shaum M. Kabadi, Brian K. Lee and Longjian Liu: Joint effects of obesity and vitamin D deficiency on insulin resistance and type 2 diabetes: Results from the NHANES 2001-2006. Diabetes Care 2012;35:2048-54, PMID: 22751957.

Longjian Liu, Ming Chen, Shelley R Hankins, Ana E. Nùñez, Robert A Watson, Perry J Weinstock, Craig J. Newschaffer, and Howard J Eisen: Serum 25-Hydroxyvitamin D Concentration and Mortality from Heart Failure and Cardiovascular Disease, and Premature Mortality from All-Cause in US Adults. . American J Cardiology. 2012;110:834-9. PMID: 22658246

Longjian Liu: Social Connections, Diabetes Mellitus, and Risk of Mortality among White and African American Adults Aged 70 and Older: An Eight-Year Follow-up Study. Annals of Epidemiology, 2011;21:26-33, PMID: 21130366.

Longjian Liu: Changes in Cardiovascular Hospitalization and Comorbidity of Heart Failure in the United States: Findings from the National Hospital Discharge Surveys 1980-2006. International Journal of Cardiology, 2011 May 19;149(1):39-45. PMID 20060181.

Longjian Liu, Jennifer A. Nettleton, Alain G. Bertoni, David A Bluemke, João A. Lima, and Moyses Szklo: Dietary Pattern, Metabolic Syndrome and Left Ventricular Mass and Systolic Function - The Multi-Ethnic Study of Atherosclerosis. American Journal of Clinical Nutrition, 2009;90:362-368. PMID: 19515735

Longjian Liu, Jixiang Ma, Xiaoyan Yin, Ellie Kelepouris, and Howard J Eisen: Global Variability in Angina Pectoris and Its Association With Body Mass Index and Poverty. Am Journal of Cardiology, 2011 Mar 1;107(5):655-61, PMID: 21184998.

Longjian Liu: Social Connections, Diabetes Mellitus, and Risk of Mortality among White and African American Adults Aged 70 and Older: An Eight-Year Follow-up Study. Annals of Epidemiology,2011 Jan;21(1):26-33, PMID: 21130366.

Longjian Liu and Craig J Newschaffer: Impact of social connections on risk of heart disease, cancer and all-cause mortality among elderly Americans: Findings from the second longitudinal study of aging (LSOA II). Archives of Gerontology and Geriatrics, 2010 Nov 8. [Epub ahead of print], PMID: 21067827.

Longjian Liu and Ana E Núñez: Cardiometabolic Syndrome and Its Association with Education, Smoking, Diet, Physical Activity, and Social Support: Findings from the Pennsylvania 2007 BRFSS Survey. Journal of Clinical Hypertension 2010;12(7):556-64. PMID: 20629821.

Longjian Liu: Changes in Cardiovascular Hospitalization and Comorbidity of Heart Failure in the United States: Findings from the National Hospital Discharge Surveys 1980-2006. International Journal of Cardiology, Jan 8, 2010 (Epub ahead of print). PMID 20060181.

Longjian Liu, Okamura T, Kadowaki T, Murakami Y, Hozawa A, Kita Y, Takashima N, Okuda N, Okayama A, Ueshima H.: Bundle branch block and other cardiovascular disease risk factors: US-Japan comparison. International J of Cardiology, (Epub ahead of print, Jan 19, 2009) 2010 Sep, 3;143(3):432-40, PMID 19157582.

Longjian Liu, Jennifer A. Nettleton, Alain G. Bertoni, David A Bluemke, João A. Lima, and Moyses Szklo: Dietary Pattern, Metabolic Syndrome and Left Ventricular Mass and Systolic Function - The Multi-Ethnic Study of Atherosclerosis. American Journal of Clinical Nutrition 2009, 90:362-368. PMID19515735.

Longjian Liu, Mizushima S, Ikeda Y, Nara Y and Yamori Y: Resting Heart Rate in Relation to Blood Pressure: Results from the World Health Organization - Cardiovascular Disease and Alimentary Comparison Study. International Journal of Cardiology, Mar 14, 2009 (Epub ahead of print), PMID 19446895.